Cerebrospinal fluid lactate level as a diagnostic biomarker for bacterial meningitis in children, International Journal of Emergency Medicine
Por um escritor misterioso
Descrição
Cerebrospinal fluid (CSF) lactate is a potential biomarker for bacterial meningitis in children. To this end, we performed a single-center retrospective cohort study of children from Sao Paulo, Brazil, with CSF pleocytosis to evaluate the ability of CSF lactate to distinguish between children with bacterial and aseptic meningitis. We determined the optimum cutoff point for CSF lactate using receiver-operator curve (ROC) analysis. We identified 451 children of whom 40 (9%) had bacterial meningitis. Children with bacterial meningitis had a higher median CSF lactate level [9.6 mmol/l, interquartile range (IQR) 3.2-38.5 mmol/l bacterial meningitis vs. 2.0 mmol/l, IQR 1.2-2.8 mmol/l aseptic meningitis]. A CSF lactate cutoff point of 3.0 mmol/l had a sensitivity of 95% [95% confidence interval (CI) 83-99%), specificity of 94% (95% CI 90-96%) and negative predictive value of 99.3% (95% CI 97.7-99.9%) for bacterial meningitis. In combination with a validated meningitis clinical prediction rule, the CSF lactate level can be used to distinguish between bacterial and aseptic meningitis in children with CSF pleocytosis.
PDF) Cerebrospinal fluid lactate level as a diagnostic biomarker for bacterial meningitis in children
Head-to-head comparison of CSF lactate concentration and other
SciELO - Brasil - Comparison of cerebrospinal fluid lactate with physical, cytological, and other biochemical characteristics as prognostic factors in acute bacterial meningitis Comparison of cerebrospinal fluid lactate with physical, cytological, and
Application of metabolomics in diagnostics and differentiation of meningitis: A narrative review with a critical approach to the literature - ScienceDirect
PDF] Diagnostic accuracy of cerebrospinal fluid lactate for differentiating bacterial meningitis from aseptic meningitis: a meta-analysis.
Cerebrospinal fluid lactate: a differential biomarker for bacterial and viral meningitis in children - ScienceDirect
African Journal of Microbiology Research - etiological and predictive factors of acute meningitis in mansoura fever hospital, egypt
The Value of Combined Measuring of the Cerebrospinal Fluid Lactate and Serum Procalcitonin in Diagnosis of Acute Bacterial Meningitis
Full article: Study of cerebrospinal fluid levels of lactate, lactate dehydrogenase and adenosine deaminase in the diagnosis and outcome of acute meningitis
Comparison between cerebrospinal fluid biomarkers for differential diagnosis of acute meningitis
USE OF SCORE AND CEREBROSPINAL FLUID LACTATE DOSAGE IN DIFFERENTIAL DIAGNOSIS OF BACTERIAL AND ASEPTIC MENINGITIS. - Abstract - Europe PMC
Cells, Free Full-Text
de
por adulto (o preço varia de acordo com o tamanho do grupo)
